In my 21' Howard with 547 ci, 1071 mooneyham,2 1050's and superchiller and Turbo 400 I use 48 % overdrive with a 12x16 steel 2 blade it runs 107-109 mph at 6200 rpm and cruises at about 35 mph at 2500 rpm. If the prop you have works good for you, you could go up on the gear to at least 37% OD. At 37% you don't have to cut the water jacket out of your V-drive. Of course I'm assuming you have a split case. I really like the larger gears. You can cruise without turning the motor very hard.