Talked to quite a few people. Seen lots run on boats and cars, and I have one on my new boat. Too early to see any disadvantages. No problems so far other than price.
Pretty much everyone I have spoken to says that they are the cats meow. They will damage a cheap fuel regulator. (Depending on which pump you get.) And like LaBlonde says, the more pressure you get to the regulator, the quicker you will go.