I put mine behind the engine and lined up the center of the turbos perpendicular to the engine. That gave me good access to the valve covers and aimed the compressors forward. Piping to the throttle bodies was pretty easy.
I really didn't consider center of gravity when figuring out the location.
If you're useing dry manifolds and turbos you'll want to keep them away from passengers as the heat is a significant factor.
Most of the turbo kits have the turbos mounted right alongside the engine and that blocks access to the valve covers. My turbos are large frame Garretts and they weigh 55# each.
What turbos are you using that weigh 70# ?