Should not be a problem. I have heard nothing but good things about the 525 engine with Whipples. The 525 has all of the good internals in it so it shouldn't be a problem. I know of several 500hp's with whipples and no problems. The 525 is basically the same motor so I wouldn't be apprehensive about purchasing a 525 with a Whipple.
Only downside is Whipple's customer service if there ever is a problem. That problem has been well documented on the boards.