This is from the Holley site. I installed a marine 750 CFM mechnaical secondaries and electric choke on my stock 454
Engine Size (CID) X Maximum RPM / 3456 =
CFM @100% Volumetric Efficiency
EXAMPLE:
350 CID X 6000 RPM = 2,100,000 / 3456 = 608 CFM
Approximately 608 CFM would be required for this engine. However, most street engines are capable of achieving only about 80% VE; a modified street engine with ported heads, headers, good intake and carburetor can achieve about 85% VE; a fully modified race engine can achieve 95% or greater VE. The CFM number arrived at with this formula must be factored by this percentage.