What size boat? What's the draft or depth in the water? How much money you got?...j/k
Water levels between Laughlin and Needles changes often and rapidly. In this area of the river anything other than a jet is problematic. My last venture from Needles North cost me about a Grand, and I got off cheap. If you've got a larger boat, I/O, then you'll need to monitor the river level before making any trip in that area.
Below Needles the water is plenty deep enough and you can make it all the way to Havasu w/o any problems. Below the Sand Bar is Speed Alley, keep the speed up and on plane and you'll be all right. There is a shallow area just at the mouth of the river to the lake, DON'T SLOW DOWN or you're screwed and you'll be walkin it in. Just sand, but I'd rather go fast than walk any day.
Have fun and be carefull in that danger zone.
Scream <--- been there, broke that